Qualification(s) available: PhD
- Entry requirements
- 2:1+
- UK fee:
- £4,596
- International fee:
- £25,100
- Full-time
- 3 years
- Part-time
- 6 years
- Start date
- July 2023, October 2023
- Application deadline
- 31 July 2023
- Project reference
- UF-AS-2022
- Location
- Loughborough
- Subject area(s)
- Mechanical, Electrical and Manufacturing Engineering
Project details
Human longevity has increased through improved nutrition, sanitation and healthcare in the last century. Research for extending the human lifespan has recently sped up and the first drug candidates have entered clinical trials. Biomarkers are highly valuable tools in assessing the efficacy of such interventions. Methylation clocks recently developed using methlyomic data have shown how useful bioinformatic approaches are to developing aging biomarkers. This project seeks to develop biomarkers that can help us to evaluate aging intervention approaches with a focus on the ability to quantify senescent cells.
The project will mix theoretical and experimental work. The experimental work will investigate the elimination of senescent cells and the restoration of stem cells in vitro and in vivo.
Ideally, the candidate will possess strong biomedical data processing skills. The candidate will design experiments, test hypotheses, develop and implement machine learning methods on multi-parametric data, including imaging, genomics, proteomics and metabolomics, for the development of biomarkers of aging and to assess longevity intervention approaches.
The School of Mechanical, Electrical and Manufacturing Engineering has seen 100% of its research impact rated as 'world-leading' or 'internationally excellent' (REF, 2021).
Supervisors
Primary supervisor:Professor Alexandra StolzingSecondary supervisor:Dr Tao Sun
Entry requirements
Our entry requirements are listed using standard UK undergraduate degree classifications i.e. first-class honours, upper second-class honours and lower second-class honours. To learn the equivalent for your country, please choose it from the drop-down below.
Entry requirements for United Kingdom
A bachelor's degree in a scientific or engineering discipline and three years of experience or an equivalent combination of education and experience required. Completed coursework in bioinformatics, biology, computer science, and statistics. A master's degree is preferred.
- Experience in scientific computing
- Perl/Python scripting, visualization and statistical analysis packages
- Experience working with omics data sets preferred
- Experience creating and using advanced machine learning algorithms and statistics
Afghanistan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Masters | 95% | 85% | 70% |
Albania
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diplomë e Nivelit të Pare (First Level (University) Diploma (from 2010) | 9.5 | 8.5 | 8 |
Algeria
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licence (4 year) / Diplome d'Inginieur d'Etat / Diplôme d'Etudes Supérieures | 16 | 14 | 12 |
Argentina
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Argentina | 8.5 | 7.5 | 6.0 |
Armenia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bakalavri Kochum | 90% | 80% | 70% |
Magistrosi Kochum | 3.9 | 3.5 | 3.0 |
Australia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Honours degree (AQF level 8) | First Class, 80% | Upper Second, 70%, H2A | Lower Second, 60%, 2B |
Ordinary degree - AQF Level 7 pass (mark 46 or 50) | High Distinction (80% or 85%) | Distinction (75% or 80%) | Distinction (70% or 75%) |
Austria
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree/ Diplomstudium / Magister degree | A (or 1.5) mit Auszeichnungbestanden | 60% or B or 3.0 (or 2) | 50% or C or 2.7 (or 3) |
Azerbaijan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bakalavr Diplomu | 4.5 | 4 | 3.5 |
Diplomu (Specialist Diploma) | 90% | 80% | 70% |
Bahamas
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree from University of the West Indies only | 1st (GPA 3.6) | 2:1 (GPA 3.0) | 2:2 (GPA 2.5) |
Bahrain
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.8 |
Bangladesh
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
BUET or 'Good Private' University - 4 year degree | BUET - 1st (70%) / 3.5 | BUET - 2nd (60%) / 3.0 | BUET - 2nd (55%) / 2.75 |
Other universities - Masters (1-2 years) following a 3 or 4 year degree | 80% / 4.0 | 65% / 3.25 | 50% / 2.5 |
Barbados
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Barbados - Degree from University of the West Indies only | 1st (GPA 3.6) | 2:1 (GPA 3.0) | 2:2 (GPA 2.5) |
Belarus
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Specialist Diploma (5Yr) | 9 | 7 | 5 |
Belgium
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bachelor degree | Magna Cum Laude | Cum Laude | 60%/12 |
Licenciaat | 80% | 70% | 60% |
Licencie | 17 | 14 | 12 |
Belize
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree from University of the West Indies only | 1st (GPA 3.6) | 2:1 (GPA 3.0) | 2:2 (GPA 2.5) |
Benin
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Maitrise | 18 | 15 or Bien | 12 or Assez Bien |
Bermuda
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree from University of the West Indies only | 1st (GPA 3.6) | 2:1 (GPA 3.0) | 2:2 (GPA 2.5) |
Bolivia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
A Licenciado, 4 years Private (public/private) | 85/78 | 75/66 | 67/55 |
Bosnia and Herzegovina
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diploma Visokog Obrazovanja / Diplomirani | 10 | 9 | 8 |
Botswana
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's degree | A or 80% | B or 70% | C or 60% |
Brazil
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Brazil - 4 yr Bacharel or Licenciado/Licenciatura or Título Profissional | 8.5 | 7.5 | 6.5 |
Brunei
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Brunei | First | Upper Second (60%/B/3.1) | Lower Second (50%/C/2.7) |
Bulgaria
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
5 yr Diploma za Zavarsheno Visshe Obrazovanie (Diploma of Completed Higher Education) | 6 | 5 | 4 |
Cambodia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 years | 90% or 9 or 4.0 | 80% or 8 or 3.5 | 70% or 7 or 3.0 |
Cameroon
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bachelor degree or Diplome d'Etudes Superiures de Commerce | 1st or 15 | 2:1 or 14 | 2:2 or 12.5 |
Diplome d'Ingenieur or Diplôme d'Ingénieur de Conception or a Maitrise or a 4 year Licence | 20 or GPA 3.7 | 20 or Bien (GPA 3.4) | 20 or Assez Bien (GPA 3.1) |
Canada
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0/percentage scale | 3.7/85% | 3.3/75% | 2.7/68% |
Out of 9 | 8 | 6 | 5 |
Out of 12 | 10 | 8 | 6 |
Chile
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Grado de Licenciado / Título (Profesional) de [subject area] (4 years) | 6 | 5.5 | 5 |
China
Students are required to have a bachelor degree (4 years) for entry to a postgraduate programme. The University uses the Shanghai Academic Ranking of World Universities to identify the required final mark, as outlined on the table below:
First class (70%) | Mid 2:1 (65%) | 2:1 (60%) | Mid 2:2 (55%) | 2:2 (50%) | |
---|---|---|---|---|---|
Shanghai Rank Top 250 | 83% | 79% | 75% | 73% | 70% |
Shanghai Rank 251-500 | 88% | 84% | 80% | 78% | 75% |
Shanghai Rank 501+ | 92% | 87% | 84% | 82% | 80% |
The University will consider students from Affiliated Colleges in the following way:
Applicants from colleges affiliated to universities in the top 250 Shanghai rankings will be considered if they have achieved or are likely to achieve final marks of 75%-84%.
Applicants from colleges affiliated to universities which are 251-500 in the Shanghai rankings will be considered if they have achieved or are likely to achieve final marks of 80%-87%.
Applicants from colleges affiliated to universities which are above 500 in the Shanghai rankings will be considered as follows:
- School of Business and Economics: not considered
- All other programmes if they have achieved or are likely to achieve final marks of 80%-87%.
Universities given special consideration
Applicants from a small number of Chinese universities that specialise in business, management, finance or creative arts will be given special consideration by the University. The full list of these universities and the Shanghai band under which they will be considered can be found below:
University | Chinese name | Considered inband |
Beijing Film Academy | 北京电影学院 | Top 250 |
Capital University of Physical Education and Sports* | 首都体育学院 | Top 250 |
Central Academy of Drama | 中央戏剧学院 | Top 250 |
Central Academy for Fine Arts | 中央美术学院 | Top 250 |
Central Conservatory of Music | 中央音乐学院 | Top 250 |
China Academy of Art | 中国美术学院 | Top 250 |
Guangxi University of Finance and Economics | 广西财经学院 | 251-500 |
Harbin University of Finance (Harbin Finance University) | 哈尔滨金融学院 | 251-500 |
Northwest University of Political Science and Law | 上海海关学院 | Top 250 |
Shanghai Customs College | 上海海关学院 | Top 250 |
Shanghai Theatre Academy | 上海戏剧学院) | Top 250 |
Tianjin Sport University* | 天津体育学院 | Top 250 |
*Special consideration for programmes in School of Sport, Exercise and Health Sciences and Institute for Sport Business only.
Students who do not meet the above requirements may occasionally be considered if they have a relevant degree, can show good grades in relevant subjects, and/or have substantial relevant work experience.
Colombia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciado / Título de [subject area] | 4.5 | 3.75 | 3.2 |
Costa Rica
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciado | 9 | 8 or 80 | 7 or 75 |
Croatia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Baccalaureus / Prvostupnik | 4.5 | 3.8 | 3.0 |
Cuba
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4-year Titulo de Licenciado / Licenciatura | 5 | 4 | 3 |
Cyprus
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Cyprus | 8.5 | 7.0 | 6.5 |
Czech Republic
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bakalár (after 2001)6 yr integrated Magistr | 1 | 1.5 | 2 |
Denmark
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
5 year Candidatus/Candidata Magisterii or Bachelor degree (7 point scale) | 12 | 10 | 7 |
Dominican Republic
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 year Licenciado | 3.8 | Magna Cum Laude 3.5 | Cum Laude 3.2 |
Título de [subject area] | - | 85% | 82% |
Ecuador
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Título de Licenciado | 8.5 | 8 | 7 |
Título de [subject area] | 85% | 80% | 70% |
Egypt
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Egypt | 3.5 | 3.2 | 2.8 |
Universities only | BA 90%, BSc 85% | BA 80%, BSc 75% | BA 65%, BSc 65% |
El Salvador
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
5 year Licenciado | 8.5 | 7.5 | 6.5 |
Título de Ingeniero | 85% | 75% | 65% |
Arquitecto | - | Muy Bueno | Bueno |
Estonia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bakalaureusekraad or Magister or Magistrikraad | 5 or A | 4 or B | 3 or C |
Ethiopia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's | A/GPA 4.0 | A/GPA 3.5 | B/GPA 2.8 |
Finland
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Kandidaattii/Kandidat (out of 3) | 3 | 2 | 1 |
Maisteri/Magister (out of 5) | 4.5 | 3 | 2.5 |
France
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licence (3 years)/ Maitrise/ Diplôme d'Ingénieur | 14 | 13 | 11 |
Georgia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4-year degree (% = new system) | 5 (95%) | 4.5 (85%) | 4 (75%) |
Germany
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
German Bachelor/ Diplom, Magister Artium / Zeugnis über den Zweiten Abschnitt der Ärztlichen Prüfung | 1.5 | 2.5 | 3.0 |
Ghana
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Ghana | First | Upper second/60% | Lower second/50% |
Greece
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Universities | 8.5 | 7.0 | 6 |
TEI and non-University Institutions | 8.5 | 7 | 6.5 |
Grenada
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree from University of West Indies - classification | 1st | 2:1 | 2:2 |
Degree from University of West Indies - grade / percentage | A | B / 75% | C / 55% |
Degree from University of West Indies - GPA | 3.6 | 3.0 | 2.0 |
Guatemala
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Liceniado / Titulo de (subject area) - 4years | 90% (public university) / 95% (private university) | 80% (public university) / 85% (private university) | 60% (public university) / 70% (private university) |
Guyana
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's | GPA 4 | GPA 3.5 | 3.0 |
Honduras
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Título de Licenciado / Grado Académico de Licenciatura (4 year degree) - GPA out of 5 | GPA 5 or 90% | GPA 4 or 80% | GPA 3.5 or 70% |
Hong Kong
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.5 |
Hungary
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Alapfokozt or Egyetemi Oklevel / Bachelor | 5 | 4 | 3 |
Iceland
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Baccalaurreatus degree or Kandidatsprof/Candidatus Mag | 8.5 | 7.5 | 6.5 |
India
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Institutions listed on the Indian Ranking of Higher Educational Institutions Framework | 65% (First) | 60% (First) | 55% (Upper second) |
All other Indian institutions | 70% (First with distinction) | 65% (First) | 60% (First) |
Indonesia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Sarjana I (S1) from A (or B) credited Universities | 3.7 (4.0) | 3.3 (3.7) | 3 (3.3) |
Iran
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Iran | 17 | 15 | 13 |
Iraq
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Iraq | 80% | 75% | 70% |
Ireland
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Republic of Ireland | First (70%) | Upper second (60%) | Lower second (50%) |
Israel
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
3 yr Bachelor Degree | 90% | 80% | 70% |
Italy
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diploma di Laurea | 109/110 | 104/110 (or 27) | 100/110 (or 26) |
Ivory Coast
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diplome d'Etude Approfondies, Diplome d'EtudeSuperieures or Diplome d'Etude Superieures | 16 | 14 (Bien) | 12 (Assez Bien) |
Jamaica
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
For degrees studied at The University of WestIndies or degrees accredited by UCJ and CCCJ | 1st (GPA 3.6) | 2:1 (GPA 3.0) or B | 2:2 (GPA 2.0) or C |
Japan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Japan | 85% | 80% or B or 3.0 | 70% or C or 2.0 |
Jordan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3 or 3.5/5 or 75% | 2.8 or 65% |
Kazakhstan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 5.0/percentage scale | 4.5 or 90% | 4 or 85% | 3.5 or 80% |
GPA 4.33 scale | 3.9 | 3.7 | 3.2 |
GPA 4.0 scale | 3.7 | 3.4 | 3 |
Kenya
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Kenya | First / 70% / A | Upper second / 60% / B | Lower second / 50% / C |
Kosovo
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Kosovo | 10 | 9 | 8 |
Kuwait
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.6 | 3.0 | 2.8 |
Latvia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Latvia | 9 | 7 | 6 |
Lebanon
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
American | 90% (3.5) | 80% (3.2) | 70% (2.8) |
French | 18 | 15 | 12 |
Liberia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's | 4.0 or 90% | 3.5 or 85% | 3 or 80% |
Libya
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
BSc Engineering, Architecture, Medicine | 85 (3.6) | 75 (3.0) | 65 (2.5) |
Other bachelor's degree from a university | 90 (4.0) | 85% (3.6) | 75% (3.0) |
Lithuania
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Lithuania | 9 | 8 | 7 |
Macau
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Macau | 1st or GPA 3.7 | 2:1 or GPA 3.0 | 2:2 or GPA 2.5 |
Macedonia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Macedonia | 10 | 9 | 8 |
Malawi
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's only | MSc 75% | MSc 70% | MSc 65% |
Malaysia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Classification | First Class | 2.1 | 2.2 |
GPA 4.0 scale | 3.5 | 3.0 | 2.8 |
Malta
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Malta | 1st (80%) | 2:1 (70%) | 2:2 (55%) |
Mauritius
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Mauritius | 1st or 70% | 2:1 or 60% | 2:2 or 50% |
Mexico
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Mexico | 9 | 8 | 7 |
Moldova
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diploma de Licenţă (Diploma of Licentiate) | 10 | 9 | 8 |
Mongolia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Диплом Специалиста (Specialist Diploma) | 90% or 3.5 | 80% or GPA 3.2 | 70% or GPA 3.0 |
Morocco
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Morocco | 17 | 15 | 13 |
Mozambique
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 year Licenciatura | 16 | 14 | 12 |
Myanmar (Burma)
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
2 year Master's degree | 5 or 85% | 5 or 75% | 4.5 or 65% |
Namibia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Namibia | 80% or A | 70% or B | 60% or C |
Nepal
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's (after 3 year bachelor degree) | 90% or 3.9 GPA | 80% or 3.8 GPA | 65% or 3.3 GPA |
Netherlands
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Netherlands | 8 | 7 | 6 |
New Zealand
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Year Honours degree (480 credits) - Level 8 | First (7.0) | Upper Second (6.0) | Lower Second (4.0) |
3 Year degree (360 credits) - Level 7 | A+ (9.0) | A- (7.0) | B+ (6.0) |
Nicaragua
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciatura (4 year) | 90% | 80% | 70% |
Nigeria
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
7 point Scale | 6 | 5 | 4 |
5 point scale | 4.5 | 3.8 | 3.5 |
4 point scale | 3.5 | 3 | 2.5 |
Norway
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Norway | A | B | C |
Oman
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.5 |
Pakistan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Year degree only (the higher of the 2 option) | A- or GPA 3.7 | B or GPA 3.0 | C+ or GPA 2.6 |
2 or 3 year bachelor's plus Master's | First (60%) | Second (55%) | Second (50%) |
Palestine
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bachelor Degree | A / 90% / 3.7 | B+ / 85% / 3.3 | B / 80% / 3.0 |
Panama
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Year Licenciado / Título de [subject area] | 91 (A) | 81 (B) | 71 (C) |
Papua New Guinea
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Papua New Guinea | 1st | 2:1 | 2:2 |
Paraguay
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Year Título de Licenciado / Título de [subject area] | 4.5 (85%) | 4 (80%) | 3.5 (75%) |
Peru
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Year Título de Licenciado / Título de [subject area] | 14 | 13 | 12 |
Philippines
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Degree from prestigious state universities or Centres of Excellence (COE) | Summa Cum Laude 4.0 / 96% / 1.0 | Magna cum Laude 3.5 / 92% / 1.5 | Cum Laude 3.0 / 87%/ 2.0 |
Poland
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bachelor Degree (post 2003) Magister (pre- 2003) | 5 | 4.5 / 4+ | 4 |
Portugal
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Portugal | 18 | 16 | 14 |
Qatar
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.8 |
Romania
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diploma de Licenta/ Diploma de Inginer | 9 | 8 | 7 |
Russia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Russia | 4.5 | 4.0 | 3.5 |
Rwanda
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 year bachelor (Hons) degree (480 credits) | 1st, 16/20 (80%) | 2:1,14/20 (70%) | 2:2, 12/20 (60%) |
Saudi Arabia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.8 |
GPA 5.0 scale | 4.5 | 3.75 | 3.5 |
Senegal
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Maitrise, Diplome d'Etude Approfondies,Diplome d'Etude Superieures or Diplome d'Etude Superieures Specialisees | 16/20 or Tres Bien | 14/20 or Bien | 12/20 or Assez Bien |
Serbia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Diplomirani/ Bachelor's degree | 9 | 8 | 7 |
Sierra Leone
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Honours degree or masters | 1st (70%) | 2:1 (60% or B) | 2:2 (50% or C) |
Singapore
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Classification | First | Upper second | Lower second |
GPA 4.0 scale | 3.7 | 3.0 | 2.7 |
GPA 5.0 scale | 4.5 | 3.5 | 3.0 |
Slovakia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Slovakia | 1.5 or B | 2.0 or C | 2.5 or C/high D |
Slovenia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Slovenia | 9.5 | 8.5 | 7 |
South Africa
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Classification | 1st | 2:1 | 2:2 |
Percentage scale | 75-100% | 70-74% | 60-69% |
South Korea
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA out of 4.5 | 4.0 / A | 3.5 / B | 3.0 / C+ |
GPA out of 4.3 | 4.0 / A | 3.0 / B | 2.7 / C+ |
Spain
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciado / Título de Ingeniero / Título de Arquitecto | 8.5 | 7 | 6.5 |
UCM grading | 3.0 | 2.0 | 1.5 |
Sri Lanka
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 year Professional degree or Bachelor Special or Honours degree | 90%, GPA 3.70 | 80%, GPA 3.30 | 70%, GPA 3.0 |
Sudan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Sudan (North and South) | 1st or 70% or B+ | 2:1 or 66% | Mid 2:2 or 60% or B |
Sweden
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Sweden | - | Overall grade of VG with a minimum of 90 credits at VG | Overall grade of G with a minimum of 90 credits at G |
Switzerland
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Switzerland | 6 | 5 | 4 |
Syria
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
State universities 4 years of study | 80% | 70% | 60% |
Private universities 4 years of study | 90% | 80% | 70% |
Taiwan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Category 1 (4 year degree) | 80% | 75% | 70% |
Category 2 (4 year degree) | 85% | 80% | 75% |
Tajikistan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Tajikistan | - | 4.5 | 4 |
Tanzania
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Tanzania | 1st | 2:1 | 2:2 |
Thailand
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.8 |
Trinidad and Tobago
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
For degrees studied at The University of West Indies or degrees accredited by ACTT | 1st or B+ or 70% | 2:1 or B or 65% | 2:2 or B- or 60% |
Tunisia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licence, Maîtrise, Diplôme National d'Ingénieu | 16 (tres bien) | 14 (bien) | 11 (assez bien) |
Turkey
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Lisans Diplomasi or a Műhendis Diplomasi | 3.5 | 3 | 2.5 |
Turkmenistan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
4 Yr Bakalavr, Specialist Diploma or Magistr | 5 | 4.5 | 4 |
Uganda
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Uganda | 1st or 4.4 | 2:1 or 3.8 | 2:2 or 3.0 |
Ukraine
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Dyplom Magistra or a Bachelors degree (11 / 5) | 4.5 | 4.0 | 3.5 |
United Arab Emirates
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.0 | 2.6 |
United States of America
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
GPA 4.0 scale | 3.5 | 3.2 | 2.8 |
Uruguay
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciado (4 year) | 10 | 9 | 8 |
Uzbekistan
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Bakalavr Diplomi / Diplomi (Specialist Diploma) | 90% or GPA 4.5 | 80% or GPA 4.0 | 70% or GPA 3.0 |
Venezuela
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Licenciado/Professional title. (4 year) | 18/20 or 8/9 | 16/20 or 7/9 | 14/20 or 6/9 |
Vietnam
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
10-point scale | 8.0 | 7.0 | 6.0 |
4-point scale | 3.5 | 3.0 | 2.8 |
Zambia
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
Master's | A or 4.0 or 80% | B+, 3.5 or 70% | B or 3.0 or 60% |
Zimbabwe
First-class honours (70%) | Upper second-class honours (60%) | Lower second-class honours (50%) | |
---|---|---|---|
3/4 year degree | 1st or 75% | 2:1 or 65% | 2:2 or 60% |
English language requirements
Applicants must meet the minimum English language requirements. Further details are available on the International website.
Fees and funding
Tuition fees for 2022/23 entry
UK fee
£4,596 Full-time degree per annum
International fee
£25,100 Full-time degree per annum
Find out more about research degree funding
Tuition fees cover the cost of your teaching, assessment and operating University facilities such as the library, IT equipment and other support services. University fees and charges can be paid in advance and there are several methods of payment, including online payments and payment by instalment. Fees are reviewed annually and are likely to increase to take into account inflationary pressures.
How to apply
All applications should be madeonline. Under programme name, select ‘Mechanical and Manufacturing Engineering’. Please quote reference number: UF-AS-2022.
Apply now
Contact us
- Call us +44 (0)1509 227577
- Email us A.Stolzing@lboro.ac.uk
- Web chats
- Register for email updates
FAQs
What are the stages of biomarker development? ›
In overview, the steps of biomarker development include: biomarker discovery, assay development and validation, clinical utility validation and clinical implementation [4].
What are the techniques for biomarker discovery? ›There are three main steps in proteomic analysis in order to identify a biomarker in a specific disease. These steps including; (1) extraction and separation of proteins, (2) identification of proteins, and (3) verification of proteins (Fig. 1) (Liu et al, 2014).
How are biomarkers created? ›Many biomarkers come from simple measurements made during a routine doctor visit, like blood pressure or body weight. Other biomarkers are based on laboratory tests of blood, urine, or tissues. Some capture changes at the molecular and cellular level by looking at genes or proteins.
What is the meaning of biomarker discovery? ›Biomarker discovery is a medical term describing the process by which biomarkers are discovered. Many commonly used blood tests in medicine are biomarkers.
What are the 5 biomarkers of aging? ›These include IGF-1 (insulin-like growth factor 1), insulin, glucose, C-reactive protein (a measure of systemic inflammation), triglycerides, and blood pressure.
What are the 4 types of biomarkers? ›Molecular, histologic, radiographic, or physiologic characteristics are types of biomarkers.
What are the three types of biomarkers? ›Diagnostic biomarkers accurately determine whether a patient has a particular disease. Genetics, proteins, and blood are the most common subgenres for diagnostic biomarkers.
What is the process of biomarker immunoassay development? ›The process involves four continuous stages including method development, exploratory method validation, “full” or extensive method validation, and in-study method validation, and the rigorous level is driven by the intended use of the assay (Table 1).
What are the phases of biomarker validation? ›- Phase 1: Preclinical exploratory studies.
- Phase 2: Clinical Assay Development for Clinical Disease.
- Phase 3: Retrospective Longitudinal Study.
- Phase 4: Prospective Screening Studies.
- Phase 5: Cancer Control Studies (RCT)
Prognostic versus predictive biomarkers
Prognostic biomarkers are associated with differential disease outcomes, but predictive biomarkers discriminate those who will respond or not respond to therapy.
What factors affect biomarkers? ›
Some biomarkers were affected by strong genetic factors, whereas others mainly by environmental or clinical factors. These variables are not always independent, such as blood pressure and use of medication, which are both related to age.
What is the main purpose of biomarkers? ›Biomarkers have many useful applications in health care, including disease prevention and detection, determination of individual disease risk, and disease monitoring. They can also be used to measure the safety or toxicity of a therapeutic regimen or certain environmental exposures.
What is biomarker testing for age? ›At what age do you actually live? The AgeMeter® calculates functional age by noninvasively testing the body's physiological biomarkers. The AgeMeter is a valuable tool for individuals researchers, and universities interested in warding off the effects of aging.
What is an example of biomarker evidence? ›Examples of biomarkers include everything from pulse and blood pressure through basic chemistries to more complex laboratory tests of blood and other tissues.
What are the possible problems in biomarker discovery? ›One of the main challenges in biomarker discovery is the high number of false discoveries. This occurs when initial scientific findings associated with a new biomarker cannot be reproduced by other laboratories or independent samples.
What are key biomarkers for aging? ›The main mechanisms identified as potential biomarkers of aging are DNA methylation, loss of histones, and histone modification. The uses for biomarkers of aging are ubiquitous and identifying a physical parameter of biological aging would allow humans to determine our true age, mortality, and morbidity.
What are the 9 biomarkers of aging? ›The scheme enumerates the nine hallmarks described in this review: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication.
What are the most important biomarkers for longevity? ›- Vitamin D. Optimal Range = 50-100 ng/dl. ...
- CRP (C-REACTIVE PROTEIN) Optimal Range < 0.5 mg/L. ...
- Hemoglobin A1C. Optimal Range = 4.6% – 5.5% ...
- Insulin. Optimal Range = 2 – 5 uIU/ml. ...
- RBC Magnesium. Optimal Range = 6 – 6.5 mg/dl. ...
- Testosterone. ...
- Triglyceride / HDL Ratio. ...
- Lipid Panel.
- Cardiac troponin. This protein is by far the most commonly used biomarker. It has the highest known sensitivity. ...
- Creatinine kinase (CK). This enzyme can also be measured several times over a 24-hour period. ...
- CK-MB. This is a subtype of CK. ...
- Myoglobin. This is a small protein that stores oxygen.
- 1) Muscle Mass.
- 2) Strength.
- 3) Basal Metabolic Rate.
- 4) Body Fat Percentage.
- 5) Aerobic Capacity.
- 6) Blood-sugar Tolerance.
- 7) Cholesterol/HDL Ratio.
- 8) Blood Pressure.
What is the perfect biomarker? ›
THE IDEAL BIOMARKER
It should be sensitive, but it should also correlate with the severity of damage. It should be accessible in the peripheral tissue; in the case of the kidney, for example, it should be measurable in either the blood or the urine.
A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.
What are key biomarkers? ›Biomarkers are molecules that indicate normal or abnormal process taking place in your body and may be a sign of an underlying condition or disease. Various types of molecules, such as DNA (genes), proteins or hormones, can serve as biomarkers, since they all indicate something about your health.
How do I start my first biomarker? ›Find the First Biomarker
The biomarker is located at Saint Joseph Hospital in a safe. To get to the room, you'll have to run around the building until you come across a ladder. Use the chipped wall next to it to climb up and jump onto the ladder. Now run into the office where the safe is located.
The Centers for Medicare & Medicaid Services (CMS) 14-day rule affects diagnostic tests ordered less than 14 days after an inpatient or outpatient discharge. The rule requires laboratories to bill the hospital for tests performed for Medicare patients within this 14-day window.
What is Phase 5 of biomarker evaluation? ›The phased process has been widely accepted by the biomarker research community. The multi-step approach includes: Phase 1 – Discovery; Phase 2 – Clinical Assay and Validation; Phase 3 – Retrospective Longitudinal; Phase 4 – Prospective Screening; and Phase 5 – Cancer Control.
Why are biomarkers important in clinical trials? ›In clinical trials, biomarkers serve a range of practical uses: Screening of patients for eligibility. Stratification into subgroups. Monitoring of responses.
What is the difference between a marker and a biomarker? ›In molecular terms biomarker is "the subset of markers that might be discovered using genomics, proteomics technologies or imaging technologies. Biomarkers play major roles in medicinal biology. Biomarkers help in early diagnosis, disease prevention, drug target identification, drug response etc.
Why do biomarkers fail? ›When conducting an experiment to identify biomarkers, it is crucial to design the experiment properly. 80-90% of all biomarker populations for the last 20 years have not and cannot be reproduced, and the main reason that biomarkers fail is that these experiments are not designed properly.
What are the benefits of biomarkers of aging? ›Individuals could use a biomarker of aging to track their biological age over time, measure the effect of diet, exercise, and drugs and predict their effects to extend lifespan or improve quality of life. Medicines could be designed and identified based on their effect on biological age.
How do biomarkers work? ›
Biomarker testing helps characterize alterations in the tumor. Biomarkers can be DNA, RNA, protein or metabolomic profiles that are specific to the tumor. Testing can include genomic testing to look at the DNA sequence, DNA or RNA tests to look for gene fusions, or tests to measure RNA or protein levels.
How long does biomarker testing take? ›Q: How long does it take to get biomarker testing results back? Liquid biopsy results take about 5-7 days. Tissue biopsy results take about 2-4 weeks (depending on if it is done in house or needs to be sent out).
What questions to ask about biomarker testing? ›3 After testing, ask these questions: “Did you test me for these biomarkers?” “What are the results of these tests?” “Can I get a copy of my test results?” If the test results are negative, ask “Should I be retested?”
Are biomarkers always accurate? ›Errors are most often made when biomarker data are over interpreted. For example, the results of one study may indicate that a specific biomarker (collected as a measure of an exposure or susceptibility) is strongly associated with a particular disease or outcome.
What is biomarker assay development? ›Assay development refers to the efforts to develop and optimize a testing system (assay) for quantifying biomarkers. Assay qualification refers to the efforts to evaluate and characterize how well this assay performs as an analytical method.
What is the regulatory pathway for biomarkers? ›Regulatory pathways for the integration of biomarkers in drug development. The US Food and Drug Administration (FDA) outlines three primary sources for biomarker evidence, which include scientific community consensus, drug-specific development and approval process, and the biomarker qualification program (Figure 2).
What is 14 3 3 biomarker? ›14-3-3η has been reported to be a novel RA-related biomarker inducing the expression of multiple factors mediating the pathogenesis of RA, and increasing the diagnostic capture when combined with rheumatoid factor and anticyclic citrullinated peptide antibody.
What does biomarker level 2 mean? ›New Level 2: Cancer Mutations with Evidence of Clinical Significance Tests for biomarkers described as cancer mutations with evidence of clinical significance enable health care professionals to use information about their patients' tumors in accordance with the clinical evidence, such as clinical evidence presented in ...
What is the criteria for a good biomarker? ›THE IDEAL BIOMARKER
It should be sensitive, but it should also correlate with the severity of damage. It should be accessible in the peripheral tissue; in the case of the kidney, for example, it should be measurable in either the blood or the urine.
These eight guideline-recommended biomarkers include EGFR mutations, ALK fusions, ROS1 fusions, BRAF V600E mutation, RET fusions, MET amplification and MET exon 14 skipping variants, and ERBB2 (HER2) mutations. Clinical practice guidelines continue to expand with the most recent version of the NCCN guidelines (v03.
What is the turnaround time for biomarker testing? ›
Median turnaround times from biomarker testing orders to results ranged from 10 to 15 days for the individual biomarkers and 18 days for NGS.
What are examples of biomarkers? ›Examples of biomarkers include everything from pulse and blood pressure through basic chemistries to more complex laboratory tests of blood and other tissues.
What is the difference between marker and biomarker? ›In molecular terms biomarker is "the subset of markers that might be discovered using genomics, proteomics technologies or imaging technologies. Biomarkers play major roles in medicinal biology. Biomarkers help in early diagnosis, disease prevention, drug target identification, drug response etc.